Invitrogen™ DAB2 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA556005

Catalog No. PIPA556005

Description

Immunogen sequence: NAFSANLNFF PTPNPDPFRD DPFTQPDQST PSSFDSLKSP DQKKENSSSS STPLSNGPLN GDVDYFGQQF DQISNRTGKQ EAQAGPWPFS SSQTQPAVRT QNGVSEREQN GFSVKSSPNP Highest antigen sequence identity to the following orthologs: Mouse - 86%, Rat - 82%.

DAB2 mRNA is expressed in normal ovarian epithelial cells but is down-regulated or absent from ovarian carcinoma cell lines. The 770-amino acid predicted protein has an overall 83% identity with the mouse p96 protein, a putative mitogen-responsive phosphoprotein; homology is strongest in the amino-terminal end of the protein in a region corresponding to the phosphotyrosine interaction domain. The down-regulation of DAB2 may play an important role in ovarian carcinogenesis. This gene was initially named DOC2 (for Differentially expressed in Ovarian Cancer) and is distinct from the DOC2A and DOC2B genes (for double C2-like domains, alpha and beta).

Specifications

• Antigen: DAB2
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: DAB2
• Gene Alias: 5730435J12Rik; AA960054; Adaptor molecule disabled-2; AI957090; C9; D15Wsu122e; D630005B22Rik; Dab, mitogen-responsive phosphoprotein, homolog 2; Dab2; DAB2, clathrin adaptor protein; differentially expressed in ovarian carcinoma 2; Differentially-expressed protein 2; disabled 2, mitogen-responsive phosphoprotein; disabled homolog 2; disabled homolog 2 mitogen-responsive phosphoprotein; disabled homolog 2, mitogen-responsive phosphoprotein; Doc2; Doc-2; DOC-2 p82 isoform; FLJ26626; Mitogen-responsive phosphoprotein; p96
• Host Species: Rabbit
• Purification Method: Antigen Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 1601
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Concentration: 0.2 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: P98082
• Gene Symbols: DAB2
• Immunogen: Recombinant protein corresponding to Human DAB2. Recombinant protein control fragment (Product #RP-102273).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG