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Invitrogen™ DAB2 Polyclonal Antibody
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Catalog No. PIPA5102914
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100 μL
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PIPA5102914 100 μL
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Catalog No. PIPA5102914 Supplier Invitrogen™ Supplier No. PA5102914
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Description

Rabbit Polyclonal Antibody

Antibody detects endogenous levels of total DAB2.

DAB2 mRNA is expressed in normal ovarian epithelial cells but is down-regulated or absent from ovarian carcinoma cell lines. The 770-amino acid predicted protein has an overall 83% identity with the mouse p96 protein, a putative mitogen-responsive phosphoprotein; homology is strongest in the amino-terminal end of the protein in a region corresponding to the phosphotyrosine interaction domain. The down-regulation of DAB2 may play an important role in ovarian carcinogenesis. This gene was initially named DOC2 (for Differentially expressed in Ovarian Cancer) and is distinct from the DOC2A and DOC2B genes (for double C2-like domains, alpha and beta).
TRUSTED_SUSTAINABILITY

Specifications

Antigen DAB2
Applications Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene DAB2
Gene Accession No. P98078, P98082
Gene Alias 5730435J12Rik; AA960054; Adaptor molecule disabled-2; AI957090; C9; D15Wsu122e; D630005B22Rik; Dab, mitogen-responsive phosphoprotein, homolog 2; Dab2; DAB2, clathrin adaptor protein; differentially expressed in ovarian carcinoma 2; Differentially-expressed protein 2; disabled 2, mitogen-responsive phosphoprotein; disabled homolog 2; disabled homolog 2 mitogen-responsive phosphoprotein; disabled homolog 2, mitogen-responsive phosphoprotein; Doc2; Doc-2; DOC-2 p82 isoform; FLJ26626; Mitogen-responsive phosphoprotein; p96
Gene Symbols DAB2
Host Species Rabbit
Immunogen A synthesized peptide derived from human DAB2(Accession P98082), corresponding to amino acid residues F738-A770.
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 13132, 1601
Target Species Human, Mouse
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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