DAND5 Monoclonal Antibody (OTI3D4), TrueMAB™, OriGene

Mouse Monoclonal Antibody

Supplier:  OriGene TA503675

Catalog No. 50-167-4515

Description

This gene encodes a member of the BMP (bone morphogenic protein) antagonist family. Like BMPs, BMP antagonists contain cystine knots and typically form homo- and heterodimers. The CAN (cerberus and dan) subfamily of BMP antagonists, to which this gene belongs, is characterized by a C-terminal cystine knot with an eight-membered ring. The antagonistic effect of the secreted protein encoded by this gene is likely due to its direct binding to BMP proteins. As an antagonist of BMP, this gene may play a role in regulating organogenesis, body patterning, and tissue differentiation. In mouse, this protein has been shown to bind Nodal and to inhibit the Nodal signaling pathway which patterns left/right body asymmetry.

Specifications

• Antigen: DAND5
• Classification: Monoclonal
• Concentration: 1 mg/mL
• Formulation: PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
• Gene Accession No.: Q8N907
• Gene Symbols: DAND5
• Immunogen: Human recombit protein fragment corresponding to amino acids 23-189 of human DAND5 produced in E.coli.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG1

• Applications: Flow Cytometry, Western Blot
• Clone: OTI3D4
• Conjugate: Unconjugated
• Gene: DAND5
• Gene Alias: CER2, CERL2, CKTSF1B3, COCO, CRL2, DANTE, GREM3, SP1
• Host Species: Mouse
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 199699
• Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
• Form: Liquid