DAND5 Rabbit anti-Human, Polyclonal, Bioss

Catalog No.	Quantity
50-198-3217	100 μL

Catalog No. 50-198-3217 Supplier Bioss Supplier No. BS14193R

Description

Rabbit Polyclonal Antibody

This gene encodes a member of the BMP (bone morphogenic protein) antagonist family. Like BMPs, BMP antagonists contain cystine knots and typically form homo- and heterodimers. The CAN (cerberus and dan) subfamily of BMP antagonists, to which this gene belongs, is characterized by a C-terminal cystine knot with an eight-membered ring. The antagonistic effect of the secreted protein encoded by this gene is likely due to its direct binding to BMP proteins. As an antagonist of BMP, this gene may play a role in regulating organogenesis, body patterning, and tissue differentiation. In mouse, this protein has been shown to bind Nodal and to inhibit the Nodal signaling pathway which patterns left/right body asymmetry.

Specifications

• Antigen: DAND5
• Applications: Immunofluorescence, Immunohistochemistry (Paraffin)
• Classification: Polyclonal
• Concentration: 1 μg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
• Gene: DAND5
• Gene Accession No.: Q8N907
• Gene Alias: CER2; CER2CRL2; cerberus 2; Cerberus like-2; cerberus-like 2; Cerberus-like protein 2; Cerl2; Cerl-2; Cerr2; CKTSF1B3; CKTSF1B3MGC126849; COCO; CRL2; Cysteine knot superfamily 1, BMP antagonist 3; DAN domain BMP antagonist family member 5; DAN domain family member 5; DAN domain family member 5, BMP antagonist; DAN domain family, member 5; DAND5; DANTE; Dte; FLJ38607; GREM3; GREM3cerberus 2; Gremlin-3; MGC126849; SP1
• Gene Symbols: DAND5
• Host Species: Rabbit
• Immunogen: KLH conjugated synthetic peptide derived from human DAND5.
• Purification Method: Protein A
• Quantity: 100 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 199699
• Target Species: Human
• Content And Storage: -20°C
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG