DAP12 Rabbit anti-Human, Polyclonal, Bioss

Rabbit Polyclonal Antibody

Supplier:  Bioss BS12630R

Catalog No. 50-198-2368

Description

DAP12 is a transmembrane adaptor protein that is non-covalently associated with several cell surface receptors on natural killer (NK), myeloid, and presumably neuronal cells. DAP12 contains an ITAM domain that preferentially recruits the protein tyrosine kinase Syk to initiate signal transduction. Deficiency of DAP12 results in reduced antigen presentation function by myeloid cells and defects in function of certain NK cell receptors in mice, as well as presenile dementia and bone cysts in humans.

Specifications

• Antigen: DAP12
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: TYROBP
• Gene Alias: DAP12; DNAX-activation protein 12; Karap; KAR-associated protein; killer cell activating receptor associated protein; killer cell activating receptor-associated protein; Killer-activating receptor-associated protein; Ly83; PLOSL; TYRO protein tyrosine kinase binding protein; TYRO protein tyrosine kinase-binding protein; TYROBP
• Host Species: Rabbit
• Purification Method: Protein A
• Regulatory Status: RUO
• Gene ID (Entrez): 7305
• Content And Storage: -20°C
• Form: Liquid

• Applications: Immunofluorescence, Western Blot
• Concentration: 1 μg/mL
• Formulation: PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
• Gene Accession No.: O43914
• Gene Symbols: TYROBP
• Immunogen: KLH conjugated synthetic peptide derived from human DAP12.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG