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DAP12 Rabbit anti-Human, Polyclonal, Bioss
SDP

Catalog No. 501980922
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100 μL
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50-198-0922 100 μL
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Catalog No. 50-198-0922 Supplier Bioss Supplier No. BS10522R
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Description

Rabbit Polyclonal Antibody

DAP12 is a transmembrane adaptor protein that is non-covalently associated with several cell surface receptors on natural killer (NK), myeloid, and presumably neuronal cells. DAP12 contains an ITAM domain that preferentially recruits the protein tyrosine kinase Syk to initiate signal transduction. Deficiency of DAP12 results in reduced antigen presentation function by myeloid cells and defects in function of certain NK cell receptors in mice, as well as presenile dementia and bone cysts in humans.

Specifications

Antigen DAP12
Applications Immunofluorescence, Immunohistochemistry (Paraffin)
Classification Polyclonal
Concentration 1 μg/mL
Conjugate Unconjugated
Formulation PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
Gene TYROBP
Gene Accession No. O43914
Gene Alias DAP12; DNAX-activation protein 12; Karap; KAR-associated protein; killer cell activating receptor associated protein; killer cell activating receptor-associated protein; Killer-activating receptor-associated protein; Ly83; PLOSL; TYRO protein tyrosine kinase binding protein; TYRO protein tyrosine kinase-binding protein; TYROBP
Gene Symbols TYROBP
Host Species Rabbit
Immunogen KLH conjugated synthetic peptide derived from human DAP12.
Purification Method Protein A
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 7305
Target Species Human
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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