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DAP3 Monoclonal Antibody (OTI3H6), TrueMAB™, OriGene
SDP

Mouse Monoclonal Antibody

Supplier:  OriGene TA802929

Encompass_Preferred

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Catalog No. 50-167-9495


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Description

Description

Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 28S subunit protein that also participates in apoptotic pathways which are initiated by tumor necrosis factor-alpha, Fas ligand, and gamma interferon. This protein potentially binds ATP/GTP and might be a functional partner of the mitoribosomal protein S27. Splice variants that differ in the 5′ UTR have been found for this gene; both variants encode the same protein. Pseudogenes corresponding to this gene are found on chromosomes 1q and 2q.
Specifications

Specifications

DAP3
Monoclonal
1 mg/mL
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
P51398
DAP3
Human recombit protein fragment corresponding to amino acids 161-398 of human DAP3 produced in E.coli.
100 μL
Primary
Human
Antibody
IgG1
Western Blot
OTI3H6
Unconjugated
DAP3
DAP-3, MRP-S29, MRPS29, S29mt, bMRP-10
Mouse
Affinity Chromatography
RUO
7818
-20° C, Avoid Freeze/Thaw Cycles
Liquid
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