Invitrogen™ DAP3 Polyclonal Antibody

Catalog No.	Quantity
PIPA596541	100 μL

Catalog No. PIPA596541 Supplier Invitrogen™ Supplier No. PA596541

Description

Rabbit Polyclonal Antibody

Immunogen sequence: HLWVKNCRDL LQSSYNKQRF DQPLEASTWL KNFKTTNERF LNQIKVQEKY VWNKRESTEK GSPLGEVVEQ GITRVRNATD AVGIVLKELK RQSSLGMFHL LVAVDGINAL WGRTTLKRED KSPIAPEELA LVHNLRKMMK NDWHGGAIVS ALSQTGSLFK PRKAYLPQEL LGKEGFDALD PFIPILVSNY NPKEFESCIQ YYLENNWLQH EKAPTEEGKK ELLFLSNANP SLLERHCAYL; Positive Samples: MCF7, Jurkat, Mouse kidney, Mouse liver; Cellular Location: Mitochondrion.

Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 28S subunit protein that also participates in apoptotic pathways which are initiated by tumor necrosis factor-alpha, Fas ligand, and gamma interferon. This protein potentially binds ATP/GTP and might be a functional partner of the mitoribosomal protein S27. Splice variants that differ in the 5' UTR have been found for this gene; both variants encode the same protein. Pseudogenes corresponding to this gene are found on chromosomes 1q and 2q.

Specifications

• Antigen: DAP3
• Applications: ELISA, Western Blot
• Classification: Polyclonal
• Concentration: 3.4 mg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene: DAP3
• Gene Accession No.: P51398, Q9ER88
• Gene Alias: 28S ribosomal protein S29, mitochondrial; 4921514D13Rik; bMRP-10; DAP3; DAP-3; death associated protein 3; death-associated protein 3; DKFZp686G12159; Ionizing radiation resistance conferring protein; MGC126058; MGC126059; mitochondrial 28S ribosomal protein S29; Mitochondrial small ribosomal subunit protein mS29; MRPS29; MRP-S29; S29mt
• Gene Symbols: DAP3
• Host Species: Rabbit
• Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 159-398 of human DAP3 (NP_3875061).
• Purification Method: Affinity Chromatography
• Quantity: 100 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 295238, 65111, 7818
• Target Species: Human, Mouse, Rat
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG