Invitrogen™ DAP3 Polyclonal Antibody

Goat Polyclonal Antibody

Supplier:  Invitrogen™ PA518042

Catalog No. PIPA518042

Description

This antibody is tested in Peptide ELISA: antibody detection limit dilution 64,000.

Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 28S subunit protein that also participates in apoptotic pathways which are initiated by tumor necrosis factor-alpha, Fas ligand, and gamma interferon. This protein potentially binds ATP/GTP and might be a functional partner of the mitoribosomal protein S27. Splice variants that differ in the 5' UTR have been found for this gene; both variants encode the same protein. Pseudogenes corresponding to this gene are found on chromosomes 1q and 2q.

Specifications

• Antigen: DAP3
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: DAP3
• Gene Alias: 28S ribosomal protein S29, mitochondrial; 4921514D13Rik; bMRP-10; DAP3; DAP-3; death associated protein 3; death-associated protein 3; DKFZp686G12159; Ionizing radiation resistance conferring protein; MGC126058; MGC126059; mitochondrial 28S ribosomal protein S29; Mitochondrial small ribosomal subunit protein mS29; MRPS29; MRP-S29; S29mt
• Host Species: Goat
• Purification Method: Ammonium sulfate precipitation
• Regulatory Status: RUO
• Gene ID (Entrez): 7818
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Concentration: 0.5 mg/mL
• Formulation: TBS with 0.5% BSA and 0.02% sodium azide; pH 7.3
• Gene Accession No.: P51398
• Gene Symbols: DAP3
• Immunogen: Synthetic peptide sequence (NPSLLERHCAYL) corresponding to the C-terminus amino acids of DAP3 (aa 387-398).
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG