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  5. R&D Systems™ Dapansutrile

R&D Systems™ Dapansutrile
SDP

Catalog No. RD10195092 Shop All Novus Products
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RD10195092 50 mg
RD10195089 10 mg
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Catalog No. RD10195092 Supplier R&D Systems™ Supplier No. 6902/50

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Description

A Tocris product, part of R&D Systems. NLRP3 inflammasome inhibitor; disrupts inflammasome formation

Dapansutrile is a NLRP3 inflammasome inhibitor that disrupts inflammasome formation. Reduces LPS/ATP-induced IL-1β secretion in human and mouse macrophages in vitro, without affecting TNFα levels. Reduces LPS-induced inflammation in vivo. Also reduces joint swelling and markers of inflammation in synovial fluid in a mouse model of acute arthritis. Displays cardioprotective effects in a mouse model of cardiac ischemic reperfusion injury.

OLT1177™ is a registered trademark of Olatec Therapeutics LLC in the United States and other countries.

Specifications

Quantity 50 mg
Product Line Tocris
Molecular Formula C4H7NO2S
Formula Weight 133.17
Product Type Inhibitor
Purity 98%
Product Title
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