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DAPK1/2 Rabbit anti-Human, Polyclonal, Bioss
SDP

Catalog No. 501984062
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Catalog No. Quantity
50-198-4062 100 μL
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Catalog No. 50-198-4062 Supplier Bioss Supplier No. BS1713R
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Description

Rabbit Polyclonal Antibody

Calcium/calmodulin-dependent serine/threonine kinase involved in multiple cellular signaling pathways that trigger cell survival, apoptosis, and autophagy. Regulates both type I apoptotic and type II autophagic cell deaths signal, depending on the cellular setting. The former is caspase-dependent, while the latter is caspase-independent and is characterized by the accumulation of autophagic vesicles. Acts as a mediator of anoikis and a suppressor of beta-catenin-dependent anchorage-independent growth of malignant epithelial cells. May play a role in granulocytic maturation. Isoform 2 is not regulated by calmodulin. It can phosphorylate MYL9. It can induce membrane blebbing and autophagic cell death.

Specifications

Antigen DAPK1/2
Applications Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 1 μg/mL
Conjugate Unconjugated
Formulation PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
Gene DAPK2
Gene Accession No. P53355, Q9UIK4
Gene Symbols DAPK1, DAPK2
Host Species Rabbit
Immunogen KLH conjugated synthetic peptide derived from human DAPK2.
Purification Method Protein A
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 1612, 23604
Target Species Human
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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