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Invitrogen™ DAPK1 Monoclonal Antibody (12B1)
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Catalog No. PIMA536128
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100 μL
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Catalog No. Quantity
PIMA536128 100 μL
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Catalog No. PIMA536128 Supplier Invitrogen™ Supplier No. MA536128
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Description

Mouse Monoclonal Antibody

DAPK1 Monoclonal Antibody for ICC/IF, IHC (P), Western Blot

DAPK1 is a large, calmodulin-dependent kinase involved in gamma-interferon induced programmed cell death and is a potential tumor suppressor. DAPK1 is involved in multiple cellular signaling pathways that trigger cell survival, apoptosis, and authophagy. It regulates both type I apoptotic and type II autophagic cell death signal, depending on the cellular setting. Type I apoptotic cell death is caspase-dependent, type II authophagic cell death is caspase-independent. DAPK1 phosphorylates PIN1 resulting in inhibition of its catalytic activity, nuclear localization, and cellular function. It also phosphorylates TPM1, STX1A, PRKD1, BECN1, TSC2, RPS6, MYL9, and DAPK3.
TRUSTED_SUSTAINABILITY

Specifications

Antigen DAPK1
Applications Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Monoclonal
Clone 12B1
Concentration 2 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.2% BSA, 50% glycerol and 0.05% sodium azide; pH 7.4
Gene DAPK1
Gene Accession No. P53355, Q80YE7
Gene Alias D13Ucla1; DAP kinase 1; DAPK; DAPK1; DAP-Kinase; death associated protein kinase 1; death-associated protein kinase 1; DKFZp781I035; OTTHUMP00000216193
Gene Symbols DAPK1
Host Species Mouse
Immunogen Recombinant protein within Human DAPK1 aa 447-683.
Purification Method Protein A
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 1612, 306722, 69635
Target Species Human, Mouse, Rat
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG1
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