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Invitrogen™ DAPK1 Monoclonal Antibody (DAPK-55)
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Catalog No. PIMA124696
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100 μL
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PIMA124696 100 μL
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Catalog No. PIMA124696 Supplier Invitrogen™ Supplier No. MA124696
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Description

Mouse Monoclonal Antibody

Recommended positive controls: Cos-7. Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

DAPK1 is a large, calmodulin-dependent kinase involved in gamma-interferon induced programmed cell death and is a potential tumor suppressor. DAPK1 is involved in multiple cellular signaling pathways that trigger cell survival, apoptosis, and authophagy. It regulates both type I apoptotic and type II autophagic cell death signal, depending on the cellular setting. Type I apoptotic cell death is caspase-dependent, type II authophagic cell death is caspase-independent. DAPK1 phosphorylates PIN1 resulting in inhibition of its catalytic activity, nuclear localization, and cellular function. It also phosphorylates TPM1, STX1A, PRKD1, BECN1, TSC2, RPS6, MYL9, and DAPK3.
TRUSTED_SUSTAINABILITY

Specifications

Antigen DAPK1
Applications Immunoprecipitation, Western Blot
Classification Monoclonal
Clone DAPK-55
Concentration 7.6 mg/mL
Conjugate Unconjugated
Formulation Ascites with 15mM sodium azide
Gene DAPK1
Gene Accession No. P53355
Gene Alias D13Ucla1; DAP kinase 1; DAPK; DAPK1; DAP-Kinase; death associated protein kinase 1; death-associated protein kinase 1; DKFZp781I035; OTTHUMP00000216193
Gene Symbols DAPK1
Host Species Mouse
Immunogen Recombinant human DAP kinase expressed in bacteria.
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 1612
Target Species Human, Monkey
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG1
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