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Invitrogen™ DAPK1 Polyclonal Antibody
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Catalog No. PIPA583502
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100 μL
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Catalog No. Quantity
PIPA583502 100 μL
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Catalog No. PIPA583502 Supplier Invitrogen™ Supplier No. PA583502
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: QNAYLNGVGD FSVWEFSGNP VYFCCYDYFA ANDPTSIHVV VFSLEEPYEI QLNQVIFWLS FLKSLVPVEE PIAFGGKLKN PLQVVLVATH ADIMNVPRPA GGEFGYDKDT SLLKEIRNRF GNDLHISNKL FVLDAGA Highest antigen sequence indentity to the following orthologs: Mouse - 96%, Rat - 96%.

DAPK1 is a large, calmodulin-dependent kinase involved in gamma-interferon induced programmed cell death and is a potential tumor suppressor. DAPK1 is involved in multiple cellular signaling pathways that trigger cell survival, apoptosis, and authophagy. It regulates both type I apoptotic and type II autophagic cell death signal, depending on the cellular setting. Type I apoptotic cell death is caspase-dependent, type II authophagic cell death is caspase-independent. DAPK1 phosphorylates PIN1 resulting in inhibition of its catalytic activity, nuclear localization, and cellular function. It also phosphorylates TPM1, STX1A, PRKD1, BECN1, TSC2, RPS6, MYL9, and DAPK3.
TRUSTED_SUSTAINABILITY

Specifications

Antigen DAPK1
Applications Immunohistochemistry (Paraffin)
Classification Polyclonal
Concentration 0.2 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene DAPK1
Gene Accession No. P53355
Gene Alias D13Ucla1; DAP kinase 1; DAPK; DAPK1; DAP-Kinase; death associated protein kinase 1; death-associated protein kinase 1; DKFZp781I035; OTTHUMP00000216193
Gene Symbols DAPK1
Host Species Rabbit
Immunogen Recombinant protein corresponding to Human DAPK1. Recombinant protein control fragment (Product #RP-102894).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 1612
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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