Invitrogen™ DATF1 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5122041

Catalog No. PIPA5122041

Description

DATF1 Polyclonal Antibody for Western Blot, ICC/IF, IHC (P)

Dio-1 (Death Inducer-Obliterator-1) is a putative transcription factor that contains two zinc finger motifs. Dio-1 translocates to the nucleus, and activates apoptosis during limb development. Programmed cell death, a highly regulated form of apoptosis, plays an important role in determining the amount of tissue, the shape, and the definition of each digit during limb development. Dio-1 expression is upregulated when an apoptotic signal is detected, and subsequently apoptosis is induced. This process is similar to the expression of NFkB and NGF in response to external signals. Dio-1 expression is suppressed by caspase inhibitors and Bcl-2 expression. This supports the theory that Dio-1 functions in the onset of programmed cell death.

Specifications

• Antigen: DATF1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: DIDO1
• Gene Alias: 6720461J16Rik; BYE1; C20orf158; D130048F08Rik; DATF1; DATF-1; death associated transcription factor 1; death inducer-obliterator 1; death inducer-obliterator-2; death inducer-obliterator-3; death-associated transcription factor 1; Death-inducer obliterator 1; dido; Dido1; DIDO2; DIDO3; DIO1; DIO-1; dJ885L7.8; KIAA0333
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 11083
• Content And Storage: -20°C
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Concentration: 500 μg/mL
• Formulation: PBS with 50% glycerol and 0.05% ProClin 300
• Gene Accession No.: Q9BTC0
• Gene Symbols: DIDO1
• Immunogen: Recombinant protein Death Inducer Obliterator 1. The antigen corresponds to amino acid range 258-455 of the target protein.
• Quantity: 20 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG