Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More
  1. Home
  2. Products
  3. Antibodies
  4. Primary Antibodies
  5. All Primary Antibodies
  6. PIMA535014

Invitrogen™ DAXX Monoclonal Antibody (CL3580)
GREENER_CHOICE

Catalog No. PIMA535014
Change view
Click to view available options
Quantity:
100 μL
1 product options available for selection
Product selection table with 1 available options. Use arrow keys to navigate and Enter or Space to select.
Catalog No. Quantity
PIMA535014 100 μL
Use arrow keys to navigate between rows. Press Enter or Space to select a product option. 1 options available.
1 options
Catalog No. PIMA535014 Supplier Invitrogen™ Supplier No. MA535014
Add to Cart
Add to Cart

Description

Mouse Monoclonal Antibody

Immunogen sequence: ARGSSSSGGK KCYKLENEKL FEEFLELCKM QTADHPEVVP FLYNRQQRAH SLFLASAEFC NILSRVLSRA RSRPAKLYVY INELCTVLKA HSAKKKLNLA PAATTSNEPS GNNPPTHLSL DPTNAENTAS QSPRTR Highest antigen sequence indentity to the following orthologs: Rat - 78%, Mouse - 76%.

This gene encodes a multifunctional protein that resides in multiple locations in the nucleus and in the cytoplasm. It interacts with a wide variety of proteins, such as apoptosis antigen Fas, centromere protein C, and transcription factor erythroblastosis virus E26 oncogene homolog 1. In the nucleus, the encoded protein functions as a potent transcription repressor that binds to sumoylated transcription factors. Its repression can be relieved by the sequestration of this protein into promyelocytic leukemia nuclear bodies or nucleoli. This protein also associates with centromeres in G2 phase. In the cytoplasm, the encoded protein may function to regulate apoptosis. The subcellular localization and function of this protein are modulated by post-translational modifications, including sumoylation, phosphorylation and polyubiquitination. Alternative splicing results in multiple transcript variants.
TRUSTED_SUSTAINABILITY

Specifications

Antigen DAXX
Applications Immunohistochemistry (Paraffin), Immunocytochemistry
Classification Monoclonal
Clone CL3580
Concentration 1.0 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene DAXX
Gene Accession No. Q9UER7
Gene Alias BING2; CENP-C binding protein; DADB-159G18.9; DAP6; Daxx; death domain associated protein; Death domain-associated protein 6; death-associated protein 6; death-domain associated protein; EAP1; ETS1-associated protein 1; Fas death domain-associated protein; Fas-binding protein; hDaxx; MGC126245; MGC126246; SMIM40; Unknown (protein for MGC:138055)
Gene Symbols DAXX
Host Species Mouse
Immunogen Recombinant protein fragment of Human DAXX (Product #RP-105369)
Purification Method Protein A
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 1616
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG1
Show More Show Less
Product Title
Select an issue

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.