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Invitrogen™ DAZ1 Polyclonal Antibody
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Catalog No. PIPA580541
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100 μL
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PIPA580541 100 μL
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Catalog No. PIPA580541 Supplier Invitrogen™ Supplier No. PA580541
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Description

Rabbit Polyclonal Antibody

This product is preservative free. It is recommended to add sodium azide to avoid contamination (final concentration 0.05%-0.1%). This antibody has specificity for Human DAZ1.

This gene is a member of the DAZ gene family and is a candidate for the human Y-chromosomal azoospermia factor. Its expression is restricted to premeiotic germ cells, particularly in spermatogonia. It encodes an RNA-binding protein that is important for spermatogenesis. Four copies of this gene are found on chromosome Y within palindromic duplications; one pair of genes is part of the P2 palindrome and the second pair is part of the P1 palindrome. Each gene contains a 2.4 kb repeat including a 72-bp exon, called the DAZ repeat; the number of DAZ repeats is variable and there are several variations in the sequence of the DAZ repeat. Each copy of the gene also contains a 10.8 kb region that may be amplified; this region includes five exons that encode an RNA recognition motif domain. This gene contains three copies of the 10.8 kb repeat. However, no transcripts containing three copies of the RRM domain have been described; thus the RefSeq for this gene contains only two RRM domains.
TRUSTED_SUSTAINABILITY

Specifications

Antigen DAZ1
Applications Immunohistochemistry (Paraffin), Immunocytochemistry
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with no preservative
Gene DAZ1
Gene Accession No. Q9NQZ3
Gene Alias DAZ; DAZ1; deleted in azoospermia 1; deleted in azoospermia protein 1; SPGY; testicular tissue protein Li 49
Gene Symbols DAZ1
Host Species Rabbit
Immunogen A synthetic peptide corresponding to the N-terminus of the Human DAZ1.
Purification Method Antigen affinity chromatography, Protein A
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 1617
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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