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DBeQ, Tocris Bioscience™

Catalog No. p-4816581
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Quantity:
10 mg
50 mg
This item is not returnable. View return policy
This item is not returnable. View return policy

Description

Selective and reversible p97 ATPase inhibitor

Selective and reversible inhibitor of p97 ATPase (VCP, IC50 = 1.5 μM). Induces executioner caspases (caspase-3 and caspase-7) rapidly. Blocks the degradation of endoplasmic reticulum-associated degradation (ERAD) reporters; also blocks autophagosome maturation and promotes accumulation of LC3-II.

Chemical Identifiers

CAS 177355-84-9
Molecular Formula C22H20N4
Molecular Weight (g/mol) 340.43
MDL Number MFCD03691820
InChI Key QAIMUUJJAJBPCL-UHFFFAOYSA-N
Synonym dbeq, n2,n4-dibenzylquinazoline-2,4-diamine, n,n'-dibenzylquinazoline-2,4-diamine, 2,4-dibencilaminoquinazoline, 2,4-quinazolinediamine, n,n'-bis phenylmethyl, n*2*,n*4*-dibenzyl-quinazoline-2,4-diamine, n2,n4-bis phenylmethyl-2,4-quinazolinediamine, jrf12, jrf 12, jrf-12
PubChem CID 676352
IUPAC Name N2,N4-dibenzylquinazoline-2,4-diamine
SMILES C(NC1=NC(NCC2=CC=CC=C2)=C2C=CC=CC2=N1)C1=CC=CC=C1

Specifications

Quantity 10 mg
Formula Weight 340.42
Percent Purity >99%
Chemical Name or Material DBeQ

Safety and Handling

Recommended Storage Store at +4°C
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