Invitrogen™ DBI Polyclonal Antibody

Catalog No.	Quantity
PIPA579138	100 μg

Catalog No. PIPA579138 Supplier Invitrogen™ Supplier No. PA579138

Description

Rabbit Polyclonal Antibody

Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 μg/mL. Positive Control - WB: human COLO320 whole cell, human A549 whole cell, human PC-3 whole cell, human HepG2 whole cell. IHC: human placenta tissue, human prostatic cancer tissue. ICC/IF: U20S cell. Flow: MCF-7 cell, PC-3 cell, THP-1 cell.

This gene encodes diazepam binding inhibitor, a protein that is regulated by hormones and is involved in lipid metabolism and the displacement of beta-carbolines and benzodiazepines, which modulate signal transduction at type A gamma-aminobutyric acid receptors located in brain synapses. The protein is conserved from yeast to mammals, with the most highly conserved domain consisting of seven contiguous residues that constitute the hydrophobic binding site for medium- and long-chain acyl-Coenzyme A esters. Diazepam binding inhibitor is also known to mediate the feedback regulation of pancreatic secretion and the postprandial release of cholecystokinin, in addition to its role as a mediator in corticotropin-dependent adrenal steroidogenesis. Three pseudogenes located on chromosomes 6, 8 and 16 have been identified. Multiple transcript variants encoding different isoforms have been described for this gene.

Specifications

• Antigen: DBI
• Applications: Flow Cytometry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Classification: Polyclonal
• Concentration: 500 μg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 4mg trehalose and 0.05mg sodium azide
• Gene: DBI
• Gene Accession No.: P07108
• Gene Alias: ACBD 1; ACBD1; ACBP; Acoabp3; acyl coenzyme A binding protein; acyl-CoA binding protein; acyl-CoA-binding protein; acyl-Coenzyme A binding domain containing 1; CCK RP; CCKRP; CCK-RP; cholecystokinin-releasing peptide, trypsin-sensitive; Dbi; diazepam binding inhibitor; Diazepam binding inhibitor (GABA receptor modulator acyl-Coenxyme A binding protein); diazepam binding inhibitor (GABA receptor modulator, acyl-CoA binding protein); Diazepam binding inhibitor (GABA receptor modulator, acyl-Coenxyme A binding protein); diazepam binding inhibitor (GABA receptor modulator, acyl-Coenzyme A binding protein); diazepam binding inhibitor, acyl-CoA binding protein; diazepam binding inhibitor, splice form 1b; diazepam-binding inhibitor; Endozepine; EP; GABA receptor modulator; LRRGT00046; MGC70414; octadecaneuropeptide; ODN; RNACOABP3; Triakontatetraneuropeptide; Ttn; valium
• Gene Symbols: DBI
• Host Species: Rabbit
• Immunogen: E. coli-derived human DBI recombinant protein (Position: S2-I87).
• Purification Method: Antigen affinity chromatography
• Quantity: 100 μg
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 1622
• Target Species: Human
• Content And Storage: -20°C
• Product Type: Antibody
• Form: Lyophilized
• Isotype: IgG