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DBI Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech
SDP

Catalog No. 501729486 Shop All Proteintech Group Inc Products
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50-172-9486 150 μL
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Catalog No. 50-172-9486 Supplier Proteintech Group Inc Supplier No. 144901AP150UL
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Rabbit Polyclonal Antibody

Diazepam Binding Inhibitor (DBI) is a highly conserved 10 kDa polypeptide which is expressed in various species range from yeast to mammals. As an inverse agonist for benzodiazepine receptors, DBI downregulates inhibitory effects of GABA. It also has potential to induce anxiety. Found in central and peripheral tissues, DBI also participates in metabolism of steroids, which has been known to partially modify GABAA receptor function in the CNS. In peripheral tissues, DBI plays regulatory roles in steroidogenesis. DBI levels have been reported to be decreased in the cerebrospinal fluid obtained from patients with Alzheimer disease.

Specifications

Antigen DBI
Applications Western Blot
Classification Polyclonal
Concentration 0.37 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene DBI
Gene Accession No. P07108, P11030, P31786
Gene Alias ACBD1, ACBP, Acyl CoA binding protein, CCK RP, DBI, Diazepam binding inhibitor, Endozepine, EP
Gene Symbols Dbi
Host Species Rabbit
Immunogen DBI Fusion Protein Ag5891
Purification Method Antigen Affinity Chromatography
Quantity 150 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 13167, 1622, 25045
Target Species Human, Mouse, Rat
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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