DBI Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Supplier:  Proteintech Group Inc 144901AP150UL

Catalog No. 50-172-9486

Description

Diazepam Binding Inhibitor (DBI) is a highly conserved 10 kDa polypeptide which is expressed in various species range from yeast to mammals. As an inverse agonist for benzodiazepine receptors, DBI downregulates inhibitory effects of GABA. It also has potential to induce anxiety. Found in central and peripheral tissues, DBI also participates in metabolism of steroids, which has been known to partially modify GABAA receptor function in the CNS. In peripheral tissues, DBI plays regulatory roles in steroidogenesis. DBI levels have been reported to be decreased in the cerebrospinal fluid obtained from patients with Alzheimer disease.

Specifications

• Antigen: DBI
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: DBI
• Gene Alias: ACBD1, ACBP, Acyl CoA binding protein, CCK RP, DBI, Diazepam binding inhibitor, Endozepine, EP
• Host Species: Rabbit
• Purification Method: Antigen Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 13167, 1622, 25045
• Content And Storage: -20°C
• Form: Liquid

• Applications: Western Blot
• Concentration: 0.37 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Accession No.: P07108, P11030, P31786
• Gene Symbols: Dbi
• Immunogen: DBI Fusion Protein Ag5891
• Quantity: 150 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG