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Invitrogen™ DBT Polyclonal Antibody
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Catalog No. PIPA555319
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100 μL
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PIPA555319 100 μL
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Catalog No. PIPA555319 Supplier Invitrogen™ Supplier No. PA555319
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: VGKPLVDIET EALKDSEEDV VETPAVSHDE HTHQEIKGRK TLATPAVRRL AMENNIKLSE VVGSGKDGRI LKEDILNYLE KQ Highest antigen sequence identity to the following orthologs: Mouse - 95%, Rat - 95%.

The branched-chain alpha-keto acid dehydrogenase complex (BCKD) is an inner-mitochondrial enzyme complex involved in the breakdown of the branched-chain amino acids isoleucine, leucine, and valine. The BCKD complex is thought to be composed of a core of 24 transacylase (E2) subunits, and associated decarboxylase (E1), dehydrogenase (E3), and regulatory subunits. This gene encodes the transacylase (E2) subunit. Mutations in this gene result in maple syrup urine disease, type 2. Alternatively spliced transcript variants have been described, but their biological validity has not been determined.
TRUSTED_SUSTAINABILITY

Specifications

Antigen DBT
Applications Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 0.3 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene Dbt
Gene Accession No. P11182, P53395
Gene Alias 52 kDa mitochondrial autoantigen of primary biliary cirrhosis; alpha-keto acid dehydrogenase precursor; BCATE2; BCKAD E2; BCKAD E2 subunit; BCKADE2; BCKAD-E2; BCOADC-E2; Branched chain 2-oxo-acid dehydrogenase complex component E2; branched chain acyltransferase, E2 component; branched-chain alpha-keto acid dehydrogenase complex component E2; branched-chain alpha-ketoacid dehydrogenase, E2 subunit; component of branched chain keto acid dehydrogenase complex; D3Wsu60e; DBT; Dihydrolipoamide acetyltransferase component of branched-chain alpha-keto acid dehydrogenase complex; Dihydrolipoamide branched chain transacylase; dihydrolipoamide branched chain transacylase E2; dihydrolipoyl transacylase; dihydrolipoyllysine-residue (2-methylpropanoyl)transferase; E2; E2 component of branched chain alpha-keto acid dehydrogenase complex; E2b; hypothetical protein LOC541388; im:7147214; lipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogenase complex, mitochondrial; lipoamide acyltransferase component of mitochondrial branched-chain alpha-keto acid dehydrogenase complex; MGC9061; mitochondrial branched chain alpha-keto acid dehydrogenase transacylase subunit (E2b); part of the BCKAD complex; que; transacylase precursor; zgc:103768
Gene Symbols Dbt
Host Species Rabbit
Immunogen Recombinant protein corresponding to Human DBT. Recombinant protein control fragment (Product #RP-94248).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 13171, 1629, 29611
Target Species Human, Mouse, Rat
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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