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Invitrogen™ DCAF6 Polyclonal Antibody
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Catalog No. PIPA589724
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100 μL
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PIPA589724 100 μL
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Catalog No. PIPA589724 Supplier Invitrogen™ Supplier No. PA589724
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: DNNNEKLSPK PGTGEPVLSL HYSTEGTTTS TIKLNFTDEW SSIASSSRGI GSHCKSEGQE ESFVPQSSVQ PPEGDSETKA PEESSEDVTK YQEGVSAENP VENHINITQS DKFTAKPLDS NSGERNDLNL DRSCGVPEES ASSEKAKEPE TSDQTSTESA TNENNTNPEP QFQTEATGPS AHEETSTRDS A; Positive Samples: HeLa, LO2; Cellular Location: Nucleus.

NRIP is a novel 860a.a nuclear protein consisting of seven conserved WD40 domains and one NLS motif. It binds to androgen and glucocorticoid receptors and up regulates their transcriptional activity, thereby functioning as a nuclear receptor coactivator. Role of NRIP has been implicated in cell growth and also in cervical and prostrate cancer thus indicating a therapeutic intervention. Northern Blot analysis detected a high expression of NRIP in skeletal muscle and testis and low expression in heart, prostrate and adrenal gland.
TRUSTED_SUSTAINABILITY

Specifications

Antigen DCAF6
Applications ELISA, Western Blot
Classification Polyclonal
Concentration 1.36 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.01% thimerosal; pH 7.3
Gene DCAF6
Gene Accession No. Q58WW2
Gene Alias 1200006M05Rik; Androgen receptor complex-associated protein; ARCAP; Dcaf6; DDB1 and CUL4 associated factor 6; DDB1- and CUL4-associated factor 6; IQ motif and WD repeat-containing protein 1; IQ motif and WD repeats 1; IQWD1; MSTP055; NRIP; nuclear receptor interaction protein; PC326; RGD1561961
Gene Symbols DCAF6
Host Species Rabbit
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 460-650 of human IQWD1 (NP_0010179771).
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 55827
Target Species Human
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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