Invitrogen™ DCAF6 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA589724

Catalog No. PIPA589724

Description

Immunogen sequence: DNNNEKLSPK PGTGEPVLSL HYSTEGTTTS TIKLNFTDEW SSIASSSRGI GSHCKSEGQE ESFVPQSSVQ PPEGDSETKA PEESSEDVTK YQEGVSAENP VENHINITQS DKFTAKPLDS NSGERNDLNL DRSCGVPEES ASSEKAKEPE TSDQTSTESA TNENNTNPEP QFQTEATGPS AHEETSTRDS A; Positive Samples: HeLa, LO2; Cellular Location: Nucleus.

NRIP is a novel 860a.a nuclear protein consisting of seven conserved WD40 domains and one NLS motif. It binds to androgen and glucocorticoid receptors and up regulates their transcriptional activity, thereby functioning as a nuclear receptor coactivator. Role of NRIP has been implicated in cell growth and also in cervical and prostrate cancer thus indicating a therapeutic intervention. Northern Blot analysis detected a high expression of NRIP in skeletal muscle and testis and low expression in heart, prostrate and adrenal gland.

Specifications

• Antigen: DCAF6
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: DCAF6
• Gene Alias: 1200006M05Rik; Androgen receptor complex-associated protein; ARCAP; Dcaf6; DDB1 and CUL4 associated factor 6; DDB1- and CUL4-associated factor 6; IQ motif and WD repeat-containing protein 1; IQ motif and WD repeats 1; IQWD1; MSTP055; NRIP; nuclear receptor interaction protein; PC326; RGD1561961
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 55827
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: ELISA, Western Blot
• Concentration: 1.36 mg/mL
• Formulation: PBS with 50% glycerol and 0.01% thimerosal; pH 7.3
• Gene Accession No.: Q58WW2
• Gene Symbols: DCAF6
• Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 460-650 of human IQWD1 (NP_0010179771).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG