Invitrogen™ DCAF7 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA577024

Catalog No. PIPA577024

Description

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

WD-repeats are motifs that are found in a variety of proteins and are characterized by a conserved core of 40-60 amino acids that commonly form a tertiary propeller structure. While proteins that contain WD-repeats participate in a wide range of cellular functions, they are generally involved in regulatory mechanisms concerning chromatin assembly, cell cycle control, signal transduction, RNA processing, apoptosis and vesicular trafficking. WDR68 (WD repeat-containing protein 68), also known as DCAF7 (DDB1- and CUL4- associated factor 7), HAN11 or WDR68, is a 342 amino acid protein that belongs to the WD repeat DCAF7 family and contains 4 WD repeats. Localizing to the cytoplasm and nucleus, WDR68 is involved in protein modification and ubiquitination pathways, and interacts directly with Dyrk1A, Dyrk1B and Dia 1. WDR68 is involved in craniofacial development, and may be involved in skin development.

Specifications

• Antigen: DCAF7
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: DCAF7
• Gene Alias: 1700012F10Rik; 2610037L01Rik; AN11; AN11 homolog; C86529; DCAF7; DDB1 and CUL4 associated factor 7; DDB1- and CUL4-associated factor 7; dirty south; dys; fj83g06; HAN11; han11l; human anthocyanin; RGD1305140; seven-WD-repeat protein of the AN11 family-1; SWAN-1; Unknown (protein for MGC:134591); WD repeat domain 68; WD repeat-containing protein 68; WD repeat-containing protein An11 homolog; wdr68; WD-repeat protein; wu:fj83g06; zgc:63940
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 10238, 303602, 71833
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: P61962, P61963
• Gene Symbols: DCAF7
• Immunogen: Recombinant full length Human DCAF7.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG