Invitrogen™ DCAMKL2 Monoclonal Antibody (2A5)

Mouse Monoclonal Antibody

Supplier:  Invitrogen™ MA523144

Catalog No. PIMA523144

Description

Peptide Sequence: FRGLKISAHG RSSSNVNGGP ELDRCISPEG VNGNRCSESS TLLEKYKIGK VIGDGNFAVV KECIDRSTGK EFALKIIDKA KCCGKEHLIE *.

DCAMKL2 is a serine/threonine kinase involved in signal transduction and cellular communication, and is the human homolog of a rat protein kinase expressed in cerebrocortical lamination that binds microtubules. The microtubule-polymerizing activity of the encoded protein is independent of its protein kinase activity. Mouse studies show that the DCX gene, another family member, and this gene share function in the establishment of hippocampal organization and that their absence results in a severe epileptic phenotype and lethality, as described in human patients with lissencephaly. Multiple alternatively spliced transcript variants have been identified.

Specifications

• Antigen: DCAMKL2
• Classification: Monoclonal
• Concentration: 0.2-1.0 mg/mL
• Formulation: PBS with no preservative; pH 7.4
• Gene Accession No.: Q8N568
• Gene Symbols: DCLK2
• Immunogen: DCLK2 (AAH32726, 348 a.a. ~ 438 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG1 κ

• Applications: ELISA, Western Blot
• Clone: 2A5
• Conjugate: Unconjugated
• Gene: DCLK2
• Gene Alias: 6330415M09Rik; AU044875; CaMK-like CREB regulatory kinase 2; CL2; CLICK2; Click-II; CLIK2; DCAMKL2; DCDC3; DCDC3B; DCK2; DCLK2; doublecortin and CaM kinase-like 2; doublecortin domain-containing protein 3B; doublecortin kinase 2; doublecortin like kinase 2; doublecortin-like and CAM kinase-like 2; Doublecortin-like kinase 2; RGD1308384; Serine/threonine-protein kinase DCLK2
• Host Species: Mouse
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 166614
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid