DCC Mouse anti-Human, Clone: OTI4A1, lyophilized, TrueMAB™

Catalog No.	Quantity
50-166-7019	100 μg

Catalog No. 50-166-7019 Supplier OriGene Supplier No. CF804515

Description

Mouse Monoclonal Antibody

Reconstitute with PBS (pH 7.3) and recommend to perform another round of desalting process using Product No. 7KMWCO

This gene encodes a netrin 1 receptor. The transmembrane protein is a member of the immunoglobulin superfamily of cell adhesion molecules, and mediates axon guidance of neuronal growth cones towards sources of netrin 1 ligand. The cytoplasmic tail interacts with the tyrosine kinases Src and focal adhesion kinase (FAK, also known as PTK2) to mediate axon attraction. The protein partially localizes to lipid rafts, and induces apoptosis in the absence of ligand. The protein functions as a tumor suppressor, and is frequently mutated or downregulated in colorectal cancer and esophageal carcinoma.

Specifications

• Antigen: DCC
• Applications: Western Blot
• Classification: Monoclonal
• Clone: OTI4A1
• Conjugate: Unconjugated
• Formulation: PBS with 8% trehalose and no preservative; pH 7.3
• Gene: DCC
• Gene Accession No.: P43146
• Gene Alias: CRC18, CRCR1, HGPPS2, IGDCC1, MRMV1, NTN1R1
• Gene Symbols: DCC
• Host Species: Mouse
• Immunogen: Full length human recombit protein of human DCC produced in HEK293T cell.
• Purification Method: Affinity Chromatography
• Quantity: 100 μg
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 1630
• Target Species: Human
• Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
• Product Type: Antibody
• Form: Lyophilized
• Isotype: IgG2b