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Tocris Bioscience™ dCeMM2
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Catalog No. 752550
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75-255-0 50 mg
75-251-0 10 mg
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Catalog No. 75-255-0 Supplier Tocris Bioscience™ Supplier No. 7525/50
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Description

Molecular glue Degrader; induces ubiquitination and degradation of cyclin K

dCeMM2 is a molecular glue degrader. Induces ubiquitination and degradation of cyclin K by eliciting an interaction of CDK12-cyclin K with a CRL4B ligase complex. dCeMM2 displays near-total degradation of protein at 2.5 μM within 2h. Cell-permeable.

Specifications

Chemical Name or Material N-(5-Chloro-2-pyridinyl)-2-(5 H-1,2,4-triazino[5,6-b]indol-3-ylthio)acetamide
CAS 296771-07-8
Quantity 50 mg
Target Molecular Glues
Molecular Formula C16H11ClN6OS
Purity 0.98
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