Invitrogen™ DCK Monoclonal Antibody (2F10)

Mouse Monoclonal Antibody

Supplier:  Invitrogen™ MA518705

Catalog No. PIMA518705

Description

Peptide Sequence: WMNNQFGQSL ELDGIIYLQA TPETCLHRIY LRGRNEEQGI PLEYLEKLHY KHESWLLHRT LKTNFDYLQE VPILTLDVNE DFKDKYESLV EKVKEFLSTL.

Deoxycytidine kinase (DCK) is required for the phosphorylation of several deoxyribonucleosides and their nucleoside analogs. Deficiency of DCK is associated with resistance to antiviral and anticancer chemotherapeutic agents. Conversely, increased deoxycytidine kinase activity is associated with increased activation of these compounds to cytotoxic nucleoside triphosphate derivatives. DCK is clinically important because of its relationship to drug resistance and sensitivity.

Specifications

• Antigen: DCK
• Classification: Monoclonal
• Concentration: 0.5 mg/mL
• Formulation: PBS with no preservative; pH 7.4
• Gene Accession No.: P27707
• Gene Symbols: DCK
• Immunogen: DCK (NP_000779, 161 a.a. ~ 260 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG2b κ

• Applications: ELISA, Western Blot, Immunocytochemistry
• Clone: 2F10
• Conjugate: Unconjugated
• Gene: DCK
• Gene Alias: DCK; Deoxycytidine kinase; deoxynucleoside kinase
• Host Species: Mouse
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 1633
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid