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Invitrogen™ DCK Polyclonal Antibody
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Catalog No. PIPA527787
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100 μL
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Catalog No. Quantity
PIPA527787 100 μL
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Catalog No. PIPA527787 Supplier Invitrogen™ Supplier No. PA527787
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Description

Rabbit Polyclonal Antibody

Recommended positive controls: 293T, A431, HeLa, HepG2, A549, H1299, PC-12, Rat2, DCK-transfected 293T. Predicted reactivity: Mouse (93%), Rat (92%), Chicken (82%), Rhesus Monkey (96%), Bovine (95%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

Deoxycytidine kinase (DCK) is required for the phosphorylation of several deoxyribonucleosides and their nucleoside analogs. Deficiency of DCK is associated with resistance to antiviral and anticancer chemotherapeutic agents. Conversely, increased deoxycytidine kinase activity is associated with increased activation of these compounds to cytotoxic nucleoside triphosphate derivatives. DCK is clinically important because of its relationship to drug resistance and sensitivity.
TRUSTED_SUSTAINABILITY

Specifications

Antigen DCK
Applications Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 1.41 mg/mL
Conjugate Unconjugated
Formulation PBS with 20% glycerol and 0.025% ProClin 300; pH 7
Gene DCK
Gene Accession No. P27707, P43346, P48769
Gene Alias DCK; Deoxycytidine kinase; deoxynucleoside kinase
Gene Symbols DCK
Host Species Rabbit
Immunogen Recombinant protein encompassing a sequence within the center region of human DCK. The exact sequence is proprietary.
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 13178, 1633, 79127
Target Species Human, Mouse, Rat
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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