Invitrogen™ DCK Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA579140

Catalog No. PIPA579140

Description

Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 μg/mL. Positive Control - WB: human Jurkat whole cell, rat thymus tissue, mouse thymus tissue. IHC: human breast cancer tissue, human ovary cancer tissue, human tonsil tissue, mouse liver tissue, rat liver tissue. Flow: U87 cell.

Deoxycytidine kinase (DCK) is required for the phosphorylation of several deoxyribonucleosides and their nucleoside analogs. Deficiency of DCK is associated with resistance to antiviral and anticancer chemotherapeutic agents. Conversely, increased deoxycytidine kinase activity is associated with increased activation of these compounds to cytotoxic nucleoside triphosphate derivatives. DCK is clinically important because of its relationship to drug resistance and sensitivity.

Specifications

• Antigen: DCK
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: DCK
• Gene Alias: DCK; Deoxycytidine kinase; deoxynucleoside kinase
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 13178, 1633, 79127
• Content And Storage: -20°C
• Form: Lyophilized

• Applications: ELISA, Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot, Western Blot
• Concentration: 500 μg/mL
• Formulation: PBS with 4mg trehalose and no preservative
• Gene Accession No.: P27707, P43346, P48769
• Gene Symbols: DCK
• Immunogen: E. coli-derived human DCK recombinant protein (Position: E17-L260).
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG