Invitrogen™ DCLK1 Monoclonal Antibody (OTI1F8)

Mouse Monoclonal Antibody

Supplier:  Invitrogen™ MA526800

Catalog No. PIMA526800

Description

DCLK1 Monoclonal Antibody for Western Blot, IHC (P)

DCAMKL1 (DCLK1) serine/threonine kinase or DCLK1 or doublecortin-like kinase 1 contains two N-terminal doublecortin domains (which bind microtubules and regulate microtubule polymerization), a C-terminal serine/threonine protein kinase domain (which shows substantial homology to Ca2+/calmodulin-dependent protein kinase), and a serine/proline-rich domain in between the doublecortin and the protein kinase domains (which mediates multiple protein-protein interactions). DCAMKL1 is a microtubule-associated kinase that can undergo autophosphorylation. DCAMKL1 has microtubule-polymerizing activity that is independent of its protein kinase activity. DCAMKL1 is involved in several different cellular processes, including neuronal migration, retrograde transport, neuronal apoptosis and neurogenesis.

Specifications

• Antigen: DCLK1
• Classification: Monoclonal
• Concentration: 1 mg/mL
• Formulation: PBS with 1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Accession No.: O08875, O15075, Q9JLM8
• Gene Symbols: DCLK1
• Immunogen: Human recombinant protein fragment corresponding to amino acids 193-492 of DCLK1 produced in E.coli.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG2b

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Clone: OTI1F8
• Conjugate: Unconjugated
• Gene: DCLK1
• Gene Alias: 1700113D08Rik; 2810480F11Rik; AI836758; Ania4; Calcium/calmodulin-dependent protein kinase type I-like CPG16; CL1; CLICK1; Click-I; CLICK-I beta; Cpg16; Dcamkl1; DCDC3A; Dcl; Dclk; Dclk1; double cortin and calcium/calmodulin-dependent protein kinase-like 1; doublecortin and calcium/calmodulin-dependent protein kinase-like 1; doublecortin domain-containing protein 3A; doublecortin like kinase 1; doublecortin-like and CAM kinase-like 1; Doublecortin-like kinase 1; KIAA0369; mKIAA0369; RP11-113P14.1; Serine/threonine-protein kinase DCLK1
• Host Species: Mouse
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 13175, 83825, 9201
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid