Invitrogen™ DCLK1 Polyclonal Antibody

Catalog No.	Quantity
PIPA578281	100 μL

Catalog No. PIPA578281 Supplier Invitrogen™ Supplier No. PA578281

Description

Rabbit Polyclonal Antibody

Positive Control: U87-MG, SK-N-SH, IMR32, SK-N-AS, mouse hippocampus, mouse brain, rat brain Predicted Reactivity: Chicken (91%) Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

DCAMKL1 (DCLK1) serine/threonine kinase or DCLK1 or doublecortin-like kinase 1 contains two N-terminal doublecortin domains (which bind microtubules and regulate microtubule polymerization), a C-terminal serine/threonine protein kinase domain (which shows substantial homology to Ca2+/calmodulin-dependent protein kinase), and a serine/proline-rich domain in between the doublecortin and the protein kinase domains (which mediates multiple protein-protein interactions). DCAMKL1 is a microtubule-associated kinase that can undergo autophosphorylation. DCAMKL1 has microtubule-polymerizing activity that is independent of its protein kinase activity. DCAMKL1 is involved in several different cellular processes, including neuronal migration, retrograde transport, neuronal apoptosis and neurogenesis.

Specifications

• Antigen: DCLK1
• Applications: Western Blot
• Classification: Polyclonal
• Concentration: 1.77 mg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 20% glycerol and 0.025% ProClin 300; pH 7
• Gene: DCLK1
• Gene Accession No.: O08875, O15075, Q9JLM8
• Gene Alias: 1700113D08Rik; 2810480F11Rik; AI836758; Ania4; Calcium/calmodulin-dependent protein kinase type I-like CPG16; CL1; CLICK1; Click-I; CLICK-I beta; Cpg16; Dcamkl1; DCDC3A; Dcl; Dclk; Dclk1; double cortin and calcium/calmodulin-dependent protein kinase-like 1; doublecortin and calcium/calmodulin-dependent protein kinase-like 1; doublecortin domain-containing protein 3A; doublecortin like kinase 1; doublecortin-like and CAM kinase-like 1; Doublecortin-like kinase 1; KIAA0369; mKIAA0369; RP11-113P14.1; Serine/threonine-protein kinase DCLK1
• Gene Symbols: DCLK1
• Host Species: Rabbit
• Immunogen: Recombinant protein encompassing a sequence within the center region of human DCLK1. The exact sequence is proprietary.
• Purification Method: Antigen Affinity Chromatography
• Quantity: 100 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 13175, 83825, 9201
• Target Species: Human, Mouse, Rat
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG