Invitrogen™ DCPS Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA587788

Catalog No. PIPA587788

Description

Immunogen sequence: MADAAPQLGK RKRELDVEEA HAASTEEKEA GVGNGTCAPV RLPFSGFRLQ KVLRESARDK IIFLHGKVNE ASGDGDGEDA VVILEKTPFQ VEQVAQLLTG SPELQLQFSN DIYSTYHLFP PRQLNDVKTT VVYPATEKHL QKYLRQDLRL IRETGDDYRN ITLPHLESQS LSIQWVYNIL DKKAEADRIV FENPDPSDGF VLIPDLKWNQ QQLDDLYLIA ICHRRGIRSL RDLTPEHLPL LRNILHQGQE AILQRYRMKG DHLRVYLHYL; Positive Samples: HT-29; Cellular Location: Cytoplasm, Nucleus.

Necessary for the complete degradation of mRNAs, both in normal mRNA turnover and in nonsense-mediated mRNA decay. Removes the 7-methyl guanine cap structure from mRNA fragments shorter than 10 nucleotides that are produced by 3'->5' exosome-mediated mRNA decay. Releases m7GMP. Can also degrade m7GDP to m7GMP. Has no activity towards mRNA molecules longer than 25 nucleotides.

Specifications

• Antigen: DCPS
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: DCPS
• Gene Alias: 5'-(N(7)-methyl 5'-triphosphoguanosine)-[mRNA] diphosphatase; ARS; Dcps; DCS1; DCS-1; decapping enzyme, scavenger; decapping scavenger enzyme; heat shock-like protein 1; HINT5; HINT-5; Hint-related 7meGMP-directed hydrolase; Histidine triad nucleotide-binding protein 5; histidine triad protein member 5; homolog of C. elegans 7meGMP-directed hydrolase dcs-1; HSL1; HSPC015; m7GpppX diphosphatase; mRNA decapping enzyme; scavenger mRNA-decapping enzyme DcpS
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 28960
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: ELISA, Western Blot
• Concentration: 2.08 mg/mL
• Formulation: PBS with 50% glycerol and 0.09% sodium azide; pH 7.3
• Gene Accession No.: Q96C86
• Gene Symbols: DCPS
• Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-270 of human DCPS (NP_0547451).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

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