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Invitrogen™ DCPS Polyclonal Antibody
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Catalog No. PIPA587788
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100 μL
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PIPA587788 100 μL
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Catalog No. PIPA587788 Supplier Invitrogen™ Supplier No. PA587788
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: MADAAPQLGK RKRELDVEEA HAASTEEKEA GVGNGTCAPV RLPFSGFRLQ KVLRESARDK IIFLHGKVNE ASGDGDGEDA VVILEKTPFQ VEQVAQLLTG SPELQLQFSN DIYSTYHLFP PRQLNDVKTT VVYPATEKHL QKYLRQDLRL IRETGDDYRN ITLPHLESQS LSIQWVYNIL DKKAEADRIV FENPDPSDGF VLIPDLKWNQ QQLDDLYLIA ICHRRGIRSL RDLTPEHLPL LRNILHQGQE AILQRYRMKG DHLRVYLHYL; Positive Samples: HT-29; Cellular Location: Cytoplasm, Nucleus.

Necessary for the complete degradation of mRNAs, both in normal mRNA turnover and in nonsense-mediated mRNA decay. Removes the 7-methyl guanine cap structure from mRNA fragments shorter than 10 nucleotides that are produced by 3'->5' exosome-mediated mRNA decay. Releases m7GMP. Can also degrade m7GDP to m7GMP. Has no activity towards mRNA molecules longer than 25 nucleotides.
TRUSTED_SUSTAINABILITY

Specifications

Antigen DCPS
Applications ELISA, Western Blot
Classification Polyclonal
Concentration 2.08 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.09% sodium azide; pH 7.3
Gene DCPS
Gene Accession No. Q96C86
Gene Alias 5'-(N(7)-methyl 5'-triphosphoguanosine)-[mRNA] diphosphatase; ARS; Dcps; DCS1; DCS-1; decapping enzyme, scavenger; decapping scavenger enzyme; heat shock-like protein 1; HINT5; HINT-5; Hint-related 7meGMP-directed hydrolase; Histidine triad nucleotide-binding protein 5; histidine triad protein member 5; homolog of C. elegans 7meGMP-directed hydrolase dcs-1; HSL1; HSPC015; m7GpppX diphosphatase; mRNA decapping enzyme; scavenger mRNA-decapping enzyme DcpS
Gene Symbols DCPS
Host Species Rabbit
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 1-270 of human DCPS (NP_0547451).
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 28960
Target Species Human
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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