Invitrogen™ DCPS Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA530566

Catalog No. PIPA530566

Description

Recommended positive controls: A549, HeLa, HepG2. Predicted reactivity: Human (99%), Mouse (87%), Rat (85%), Pig (87%), Bovine (87%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

Necessary for the complete degradation of mRNAs, both in normal mRNA turnover and in nonsense-mediated mRNA decay. Removes the 7-methyl guanine cap structure from mRNA fragments shorter than 10 nucleotides that are produced by 3'->5' exosome-mediated mRNA decay. Releases m7GMP. Can also degrade m7GDP to m7GMP. Has no activity towards mRNA molecules longer than 25 nucleotides.

Specifications

• Antigen: DCPS
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: DCPS
• Gene Alias: 5'-(N(7)-methyl 5'-triphosphoguanosine)-[mRNA] diphosphatase; ARS; Dcps; DCS1; DCS-1; decapping enzyme, scavenger; decapping scavenger enzyme; heat shock-like protein 1; HINT5; HINT-5; Hint-related 7meGMP-directed hydrolase; Histidine triad nucleotide-binding protein 5; histidine triad protein member 5; homolog of C. elegans 7meGMP-directed hydrolase dcs-1; HSL1; HSPC015; m7GpppX diphosphatase; mRNA decapping enzyme; scavenger mRNA-decapping enzyme DcpS
• Host Species: Rabbit
• Purification Method: Antigen Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 28960
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Concentration: 1 mg/mL
• Formulation: PBS with 1% BSA, 20% glycerol and 0.01% thimerosal; pH 7
• Gene Accession No.: Q96C86
• Gene Symbols: DCPS
• Immunogen: Recombinant protein fragment corresponding to a region within amino acids 1 and 149 of Human DCPS.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov