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DCT Rabbit anti-Human, Mouse, Non-human primate, Rat, Polyclonal, Proteintech
SDP

Catalog No. 501728483 Shop All Proteintech Group Inc Products
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Catalog No. 50-172-8483 Supplier Proteintech Group Inc Supplier No. 130951AP150UL
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Rabbit Polyclonal Antibody

The TYR-related proteins, TRP1 and TRP2, are also specifically expressed in melanocytes, and they likewise contribute to the synthesis of melanin within the melanosomes. The TRPs, including TYR, all share a similar transmembrane region, contain two metal-binding regions and a cysteinerich epidermal growth factor motif, and are localized in the melanosomal membrane. These proteins, however, have distinct catalytic activity, and they individually contribute to the biosynthesis of melanin biopolymers. The TRPs are believed to exist as a multi-enzyme complex, as these proteins form aggregates together, and the expression of TRP1 also helps stabilize TYR in melanocytes.

Specifications

Antigen DCT
Applications Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Classification Polyclonal
Concentration 0.17 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene DCT
Gene Accession No. P29812, P40126
Gene Alias DCT, DT, L dopachrome Delta isomerase, L dopachrome tautomerase, TRP 2, TRP2, Tyrosinase related protein 2, TYRP2
Gene Symbols Dct
Host Species Rabbit
Immunogen DCT Fusion Protein Ag3714
Purification Method Antigen Affinity Chromatography
Quantity 150 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 13190, 1638, 290484
Target Species Human, Mouse, Non-human Primate, Rat
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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