Invitrogen™ DCTD Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA596466

Catalog No. PIPA596466

Description

Immunogen sequence: MSEVSCKKRD DYLEWPEYFM AVAFLSAQRS KDPNSQVGAC IVNSENKIVG IGYNGMPNGC SDDVLPWRRT AENKLDTKYP YVCHAELNAI MNKNSTDVKG CSMYVALFPC NECAKLIIQA GIKEVIFMSD KYHDSDEATA ARLLFNMAGV TFRKFIPKCS KIVIDFDSIN SRPSQKLQ; Positive Samples: SW620, Mouse heart, Rat heart.

The protein encoded by this gene catalyzes the deamination of dCMP to dUMP, the nucleotide substrate for thymidylate synthase. The encoded protein is allosterically activated by dCTP and inhibited by dTTP, and is found as a homohexamer. This protein uses zinc as a cofactor for its activity. Two transcript variants encoding different isoforms have been found for this gene.

Specifications

• Antigen: DCTD
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: DCTD
• Gene Alias: 6030466N05Rik; dCMP deaminase; Dctd; Deoxycytidylate deaminase
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 1635, 290741, 320685
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: ELISA, Immunohistochemistry (Paraffin), Western Blot
• Concentration: 0.43 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Accession No.: P32321, Q5M9G0, Q8K2D6
• Gene Symbols: DCTD
• Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-178 of human DCTD (NP_0019122).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

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