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DCTN2 Polyclonal Antibody, Bethyl Laboratories

Catalog No. 501565275
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50-156-5275 20 μL
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Catalog No. 50-156-5275 Supplier Bethyl Laboratories, Inc Supplier No. A303489AT
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Description

Rabbit Polyclonal Antibody

The recommended shelf life for this product is 1 year from date of receipt. Application Note: For IHC, epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.

This gene encodes a 50-kD subunit of dynactin, a macromolecular complex consisting of 10-11 subunits ranging in size from 22 to 150 kD. Dynactin binds to both microtubules and cytoplasmic dynein. It is involved in a diverse array of cellular functions, including ER-to-Golgi transport, the centripetal movement of lysosomes and endosomes, spindle formation, chromosome movement, nuclear positioning, and axonogenesis. This subunit is present in 4-5 copies per dynactin molecule. It contains three short alpha-helical coiled-coil domains that may mediate association with self or other dynactin subunits. It may interact directly with the largest subunit (p150) of dynactin and may affix p150 in place.

Specifications

Antigen DCTN2
Applications Immunohistochemistry, Western Blot
Classification Polyclonal
Conjugate Unconjugated
Formulation TBS with 0.1% BSA and 0.09% sodium azide
Gene DCTN2
Gene Accession No. Q13561
Gene Alias DCTN50, DYNAMITIN, RBP50, 50 kD dynein-associated polypeptide, 50 kDa dynein-associated polypeptide, dynactin complex 50 kD subunit, dynactin complex 50 kDa subunit, dynactin subunit 2, p50 dynamitin
Gene Symbols DCTN2
Host Species Rabbit
Immunogen Between 351 and 401
Purification Method Antigen affinity chromatography
Quantity 20 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 10540
Target Species Human
Content And Storage 4° C
Product Type Antibody
Form Liquid
Isotype IgG
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