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Invitrogen™ DcTRAILR1 Polyclonal Antibody
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Catalog No. PIPA129849
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100 μg
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Catalog No. Quantity
PIPA129849 100 μg
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Catalog No. PIPA129849 Supplier Invitrogen™ Supplier No. PA129849
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Description

Rabbit Polyclonal Antibody

PA1-29849 detects DcTRAILR1 from mouse samples.

Mouse DcTRAILR1 and DcTRAILR2 (decoy TRAIL receptors 1 and 2) proteins are receptors for TRAIL according to ligand-receptor binding assays (Schneider et al. 2001). However, overexpression does not cause NF-kB activation or apoptosis, as would be expected of a TRAIL receptor. These observations led researchers to refer to these receptors as decoys. It is thought that cells that express decoy TRAIL receptor decoys at high levels relative to actual TRAIL receptors may use decoys as protection against the cytotoxic action of TRAIL (reviewed in Bouralexis et al. 2005). Additional analysis of these two murine TRAIL decoy receptors should help faciliate the understanding of the complex biology underlying TRAIL ligand/receptor interactions. DcTRAILR1 is an amino acid protein of 176 amino acids (GenBank no: NP-077252.2). DcTRAILR2 is an amino acid protein of 198 amino acids (GenBank no: AAN87807.1).
TRUSTED_SUSTAINABILITY

Specifications

Antigen DcTRAILR1
Applications Western Blot
Classification Polyclonal
Concentration 0.5 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.2% gelatin and 0.05% sodium azide
Gene Tnfrsf23
Gene Accession No. Q9ER63
Gene Alias Dctrailr1; Decoy TRAIL receptor 1; mDcTRAILR1; MGC123882; MGC123883; mSOB; SOB; TNF receptor family member SOB; TNF receptor homolog 1; Tnfrh1; Tnfrsf1al1; Tnfrsf23; TNFRSFH23; Tumor necrosis factor receptor p60 homolog 1; Tumor necrosis factor receptor superfamily member 23; tumor necrosis factor receptor superfamily, member 23
Gene Symbols Tnfrsf23
Host Species Rabbit
Immunogen Synthetic peptide corresponding to amino acids 155-168 (CSSSVSNPRNWLFL) of mouse DcTrailR1.
Purification Method Protein G
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 79201
Target Species Mouse
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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