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DCUN1D5 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech
Rabbit Polyclonal Antibody
Supplier: Proteintech Group Inc 148101AP150UL
Description
Conjugation of Nedd8 to a cullin protein, termed neddylation, is an evolutionarily conserved process that functions to activate the cullin-RING family E3 ubiquitin ligases, leading to increased proteasomal degradation of a wide range of substrate proteins. Cellular neddylation requires the action of DCN1 (Defective in cullin neddylation protein 1), which, in humans, consists of five homologues designated as DCNL1-5. DCUN1D5 gene encodes the 28 kDa DCUN1 domain-containing protein 5 containing a C-terminal potentiating neddylation domain. The cellular function of DCUN1D5 needs to be explored, recently, a mono-ubiquitination-mediated mechanism that governs nuclear-cytoplasmic trafficking of hDCNL1, was reported to regulate hDCNL1-dependent activation of the cullin-RING E3 ubiquitin ligases in selected cellular compartments.Specifications
DCUN1D5 | |
Polyclonal | |
Unconjugated | |
DCUN1D5 | |
DCN1 like protein 5, DCUN1D5 | |
Rabbit | |
Antigen Affinity Chromatography | |
RUO | |
315405, 76863, 84259 | |
-20°C | |
Liquid |
Immunocytochemistry, Immunofluorescence, Immunoprecipitation, Western Blot | |
0.29 mg/mL | |
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3 | |
Q5PPL2, Q9BTE7, Q9CXV9 | |
Dcun1d5 | |
DCUN1D5 Fusion Protein Ag6534 | |
150 μL | |
Primary | |
Human, Mouse, Rat | |
Antibody | |
IgG |
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