DCX Mouse anti-Human, Clone: OTI4A3, lyophilized, TrueMAB™

Mouse Monoclonal Antibody

Supplier:  OriGene CF501778

Catalog No. 50-166-0759

Description

Reconstitute with PBS (pH 7.3) and recommend to perform another round of desalting process using Product No. 7KMWCO

In the developing cortex, cortical neurons must migrate over long distances to reach the site of their final differentiation. DCX is a cytoplasmic protein which appears to direct neuronal migration by regulating the organization and stability of microtubules. It contains two doublecortin domains, which bind microtubules. In addition, this protein interacts with LIS1, the regulatory gamma subunit of platelet activating factor acetylhydrolase, and this interaction is important to proper microtubule function in the developing cortex. Mutations in the gene encoding DCX are a cause of X-linked lissencephaly.

Specifications

• Antigen: DCX
• Classification: Monoclonal
• Conjugate: Unconjugated
• Gene: DCX
• Gene Alias: DBCN, DC, LISX, SCLH, XLIS
• Host Species: Mouse
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 1641
• Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
• Form: Lyophilized

• Applications: Flow Cytometry, Immunocytochemistry, Immunofluorescence, Western Blot
• Clone: OTI4A3
• Formulation: PBS with 8% trehalose and no preservative; pH 7.3
• Gene Accession No.: O43602
• Gene Symbols: DCX
• Immunogen: Full length human recombit protein of human DCX produced in HEK293T cell.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG1