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DCX Mouse anti-Human, Clone: OTI4A3, lyophilized, TrueMAB™
SDP

Mouse Monoclonal Antibody

Supplier:  OriGene CF501778

Encompass_Preferred

Catalog No. 50-166-0759


May include imposed supplier surcharges.
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Description

Description

Reconstitute with PBS (pH 7.3) and recommend to perform another round of desalting process using Product No. 7KMWCO

In the developing cortex, cortical neurons must migrate over long distances to reach the site of their final differentiation. DCX is a cytoplasmic protein which appears to direct neuronal migration by regulating the organization and stability of microtubules. It contains two doublecortin domains, which bind microtubules. In addition, this protein interacts with LIS1, the regulatory gamma subunit of platelet activating factor acetylhydrolase, and this interaction is important to proper microtubule function in the developing cortex. Mutations in the gene encoding DCX are a cause of X-linked lissencephaly.
Specifications

Specifications

DCX
Monoclonal
Unconjugated
DCX
DBCN, DC, LISX, SCLH, XLIS
Mouse
Affinity Chromatography
RUO
1641
-20° C, Avoid Freeze/Thaw Cycles
Lyophilized
Flow Cytometry, Immunocytochemistry, Immunofluorescence, Western Blot
OTI4A3
PBS with 8% trehalose and no preservative; pH 7.3
O43602
DCX
Full length human recombit protein of human DCX produced in HEK293T cell.
100 μg
Primary
Human
Antibody
IgG1
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