DCX Rabbit anti-Human, Mouse, Polyclonal, Proteintech

Catalog No.	Quantity
50-172-9096	150 μL

Catalog No. 50-172-9096 Supplier Proteintech Group Inc Supplier No. 139251AP150UL

Description

Rabbit Polyclonal Antibody

Anti-DCX antibodies are widely used for detection of neurogenesis. It is also a common neuron marker since its expression is specific to neurons.

In the developing cortex, cortical neurons must migrate over long distances to reach the site of their final differentiation. DCX is a cytoplasmic protein which appears to direct neuronal migration by regulating the organization and stability of microtubules. It contains two doublecortin domains, which bind microtubules. In addition, this protein interacts with LIS1, the regulatory gamma subunit of platelet activating factor acetylhydrolase, and this interaction is important to proper microtubule function in the developing cortex. Mutations in the gene encoding DCX are a cause of X-linked lissencephaly.

Specifications

• Antigen: DCX
• Applications: Immunocytochemistry, Immunofluorescence, Western Blot
• Classification: Polyclonal
• Concentration: 0.33 mg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene: DCX
• Gene Accession No.: O43602, O88809
• Gene Alias: DBCN, DC, DCX, doublecortin, Doublin, Lis X, Lissencephalin X, LISX, SCLH, XLIS
• Gene Symbols: DCX
• Host Species: Rabbit
• Immunogen: DCX Fusion Protein Ag4945
• Purification Method: Antigen Affinity Chromatography
• Quantity: 150 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 13193, 1641
• Target Species: Human, Mouse
• Content And Storage: -20°C
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG