DDB1 Mouse anti-Human, Mouse, Rat, Clone: 4F6C6, Proteintech

Mouse Monoclonal Antibody

Supplier:  Proteintech Group Inc 660101IG150UL

Catalog No. 50-173-6453

Description

This antibody is specific to DDB1.

This gene encodes the large subunit of DNA damage-binding protein which is a heterodimer composed of a large and a small subunit. This protein functions in nucleotide-excision repair. Its defective activity causes the repair defect in the patients with xeroderma pigmentosum complementation group E (XPE). However, it remains for mutation analysis to demonstrate whether the defect in XPE patients is in this gene or the gene encoding the small subunit. In addition, Best vitelliform mascular dystrophy is mapped to the same region as this gene on 11q, but no sequence alternations of this gene are demonstrated in Best disease patients.

Specifications

• Antigen: DDB1
• Classification: Monoclonal
• Concentration: 0.43 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Accession No.: Q16531, Q3U1J4, Q9ESW0
• Gene Symbols: Ddb1
• Immunogen: DDB1 Fusion Protein Ag17903
• Quantity: 150 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG2b

• Applications: Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
• Clone: 4F6C6
• Conjugate: Unconjugated
• Gene: DDB1
• Gene Alias: DDB p127 subunit, DDB1, DDBA, DNA damage binding protein 1, DNA damage binding protein a, HBV X associated protein 1, UV damaged DNA binding factor, UV DDB 1, UV DDB1, XAP 1, XAP1, XPCE, XPE, XPE BF, XPE binding factor
• Host Species: Mouse
• Purification Method: Protein A
• Regulatory Status: RUO
• Gene ID (Entrez): 13194, 1642, 64470
• Content And Storage: -20°C
• Form: Liquid