Invitrogen™ DDB1 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA579142

Catalog No. PIPA579142

Description

Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 μg/mL. Positive Control - WB: human Hela whole cell, human HepG2 whole cell, human HEK293 whole cell, human K562 whole cell, human Raji whole cell, human CACO-2 whole cell, human THP-1 whole cell, rat brain tissue, rat kidney tissue, rat C6 whole cell, mouse brain tissue, mouse kidney tissue, mouse testis tissue. IHC: Mouse Liver tissue, Rat Liver tissue, Human Intestinal Cancer tissue IHC-F: human placenta tissue. ICC/IF: A431 cell, A549 Cell, PC-3 Cell, SMMC-7721 Cell. Flow: 293T cell.

The DNA damage-binding protein from HeLa cells is associated with polypeptides of relative mass 124,000 (DDB1) and 41,000 (DDB2) as determined by SDS-polyacrylamide gels. To test whether the DNA-repair defect in the subset of XPE patients that lack DNA damage-binding activity is caused by a defect in DDB, Keeney et al. (1994) injected purified human DDB protein into XPE cells.

Specifications

• Antigen: DDB1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: DDB1
• Gene Alias: 127kDa; AA408517; damage specific DNA binding protein 1; damaged-DNA recognition protein 1; damage-specific DNA binding protein 1, 127kDa; damage-specific DNA-binding protein 1; damage-specific DNA-binding protein, DNA repair; DDB p127 subunit; DDB1; DDBa; DNA damage-binding protein 1; DNA damage-binding protein a; DNA repair protein; HBV X-associated protein 1; p127-Ddb1; UV-damaged DNA-binding factor; UV-damaged DNA-binding protein 1; UV-DDB 1; UV-DDB1; XAP1; XAP-1; xeroderma pigmento; Xeroderma pigmentosum group E-complementing protein; XPCE; XPE; XPE-BF; XPE-binding factor
• Host Species: Rabbit
• Purification Method: Antigen Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 13194, 1642, 64470
• Content And Storage: -20°C
• Form: Lyophilized

• Applications: Flow Cytometry, Immunohistochemistry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Concentration: 500 μg/mL
• Formulation: PBS with 5mg BSA and 0.05mg sodium azide
• Gene Accession No.: Q16531, Q3U1J4, Q9ESW0
• Gene Symbols: DDB1
• Immunogen: E.coli-derived human DDB1 recombinant protein (Position: S1011-H1140).
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG