DDIT3 Monoclonal Antibody (OTI4C4), TrueMAB™, OriGene

Mouse Monoclonal Antibody

Supplier:  OriGene TA802207

Catalog No. 50-167-9150

Description

GADD153 is a small nuclear protein that is capable of dimerizing with transcription factors C/EBP alpha and beta. Once dimerized, this complex inhibits the normal binding and function of C/EBP to classical binding sites. Inversely, the C/EBP GADD153 dimer gains binding activity to other non classical C/EBP stress related targets. Under normal cellular conditions this protein is not expressed in detectable levels, but is highly unregulated during times of cellular/ER stress. Examples of GADD153 inducing stress include: treatment with tunicamycin, nutrient starvation and reducing agents that interfere with the calcium flux across the ER membrane.

Specifications

• Antigen: DDIT3
• Classification: Monoclonal
• Concentration: 1 mg/mL
• Formulation: PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
• Gene Accession No.: P35638
• Gene Symbols: DDIT3
• Immunogen: Full length human recombit protein of human DDIT3 produced in E.coli.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG2a

• Applications: Western Blot
• Clone: OTI4C4
• Conjugate: Unconjugated
• Gene: DDIT3
• Gene Alias: C/EBPzeta, CEBPZ, CHOP, CHOP-10, CHOP10, GADD153
• Host Species: Mouse
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 1649
• Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
• Form: Liquid