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DDIT3 Mouse anti-Human, Clone: OTI4G2, lyophilized, TrueMAB™
SDP

Mouse Monoclonal Antibody

Supplier:  OriGene CF802206

Encompass_Preferred

Catalog No. 50-166-5904


May include imposed supplier surcharges.
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Description

Description

Reconstitute with PBS (pH 7.3) and recommend to perform another round of desalting process using Product No. 7KMWCO

GADD153 is a small nuclear protein that is capable of dimerizing with transcription factors C/EBP alpha and beta. Once dimerized, this complex inhibits the normal binding and function of C/EBP to classical binding sites. Inversely, the C/EBP GADD153 dimer gains binding activity to other non classical C/EBP stress related targets. Under normal cellular conditions this protein is not expressed in detectable levels, but is highly unregulated during times of cellular/ER stress. Examples of GADD153 inducing stress include: treatment with tunicamycin, nutrient starvation and reducing agents that interfere with the calcium flux across the ER membrane.
Specifications

Specifications

DDIT3
Monoclonal
Unconjugated
DDIT3
C/EBPzeta, CEBPZ, CHOP, CHOP-10, CHOP10, GADD153
Mouse
Affinity Chromatography
RUO
1649
-20° C, Avoid Freeze/Thaw Cycles
Lyophilized
Western Blot
OTI4G2
PBS with 8% trehalose and no preservative; pH 7.3
P35638
DDIT3
Full length human recombit protein of human DDIT3 produced in E.coli.
100 μg
Primary
Human
Antibody
IgG1
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