DDIT3 Mouse anti-Human, Clone: OTI4G2, lyophilized, TrueMAB
Mouse Monoclonal Antibody
Manufacturer: OriGene CF802206
Reconstitute with PBS (pH 7.3) and recommend to perform another round of desalting process using Product No. 7KMWCOGADD153 is a small nuclear protein that is capable of dimerizing with transcription factors C/EBP alpha and beta. Once dimerized, this complex inhibits the normal binding and function of C/EBP to classical binding sites. Inversely, the C/EBP GADD153 dimer gains binding activity to other non classical C/EBP stress related targets. Under normal cellular conditions this protein is not expressed in detectable levels, but is highly unregulated during times of cellular/ER stress. Examples of GADD153 inducing stress include: treatment with tunicamycin, nutrient starvation and reducing agents that interfere with the calcium flux across the ER membrane.
|Full length human recombit protein of human DDIT3 produced in E.coli.|
|PBS with 8% trehalose and no preservative; pH 7.3|
|C/EBPzeta, CEBPZ, CHOP, CHOP-10, CHOP10, GADD153|
|-20° C, Avoid Freeze/Thaw Cycles|
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