Invitrogen™ DDOST Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA597181

Catalog No. PIPA597181

Description

Immunogen sequence: VCASGPRTLV LLDNLNVRET HSLFFRSLKD RGFELTFKTA DDPSLSLIKY GEFLYDNLII FSPSVEDFGG NINVETISAF IDGGGSVLVA ASSDIGDPLR ELGSECGIEF DEEKTAVIDH HNYDISDLGQ HTLIVADTEN LLKAPTIVGK SSLNPILFRG VGMVADPDNP LVLDILTGSS TSYSFFPDKP ITQYPHAVGK NTLLIAGLQA RNNARVIFSG SLDFFSDSFF NSAVQKAAPG SQRYSQTGNY ELAVALSRWV F; Positive Samples: U-87MG, HT-29, HepG2, A-549, Mouse kidney, Mouse liver, Mouse brain, Rat testis; Cellular Location: Endoplasmic reticulum membrane, Single-pass type I membrane protein.

This gene encodes a component of the oligosaccharyltransferase complex which catalyzes the transfer of high-mannose oligosaccharides to asparagine residues on nascent polypeptides in the lumen of the rough endoplasmic reticulum. The protein complex co-purifies with ribosomes. The product of this gene is also implicated in the processing of advanced glycation end products (AGEs), which form from non-enzymatic reactions between sugars and proteins or lipids and are associated with aging and hyperglycemia.

Specifications

• Antigen: DDOST
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: DDOST
• Gene Alias: advanced glycation endproduct receptor 1; advanced glycation end-product receptor 1; AGER1; AGE-R1; CDG1R; Ddost; DDOST 48 kDa subunit; dolichyl-diphosphooligosaccharide protein glycosyltransferase; dolichyl-diphosphooligosaccharide-protein glycosyltransferase; dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit; dolichyl-diphosphooligosaccharide--protein glycosyltransferase non-catalytic subunit; dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit (non-catalytic); dolichyl-di-phosphooligosaccharide-protein glycotransferase; dolichyl-diphosphooligosaccharide-protein glycotransferase; KIAA0115; MGC2191; OK/SW-cl.45; OKSWcl45; oligosaccharyl transferase 48 kDa subunit; oligosaccharyltransferase 48 kDa subunit; oligosaccharyltransferase OST48; oligosaccharyltransferase subunit 48; OST; OST48; WBP1; wu:fa11d01; zgc:66068; zgc:66068 protein; zgc:77478
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 13200, 1650, 313648
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: ELISA, Immunohistochemistry (Paraffin), Western Blot
• Concentration: 2.88 mg/mL
• Formulation: PBS with 50% glycerol and 0.01% thimerosal; pH 7.3
• Gene Accession No.: O54734, P39656, Q641Y0
• Gene Symbols: DDOST
• Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 40-300 of human DDOST (NP_0052072).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

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