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DDR2 Mouse anti-Human, Clone: 3E5, Bioss
SDP

Catalog No. 501989966
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100 μL
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50-198-9966 100 μL
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Catalog No. 50-198-9966 Supplier Bioss Supplier No. BSM51147M
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Description

Mouse Monoclonal Antibody

Tyrosine kinase that functions as cell surface receptor for fibrillar collagen and regulates cell differentiation, remodeling of the extracellular matrix, cell migration and cell proliferation. Required for normal bone development. Regulates osteoblast differentiation and chondrocyte maturation via a signaling pathway that involves MAP kinases and leads to the activation of the transcription factor RUNX2. Regulates remodeling of the extracellular matrix by up-regulation of the collagenases MMP1, MMP2 and MMP13, and thereby facilitates cell migration and tumor cell invasion. Promotes fibroblast migration and proliferation, and thereby contributes to cutaneous wound healing.

Specifications

Antigen DDR2
Applications Western Blot
Classification Monoclonal
Clone 3E5
Concentration 1 μg/mL
Conjugate Unconjugated
Formulation Ascites with 0.09% sodium azide; pH
Gene Ddr2
Gene Accession No. Q16832
Gene Alias AW495251; CD_antigen: CD167b; CD167 antigen-like family member B; CD167b; CD167b antigen; cell migration-inducing protein 20; Ddr2; Discoidin domain receptor 2; discoidin domain receptor family, member 2; discoidin domain receptor tyrosine kinase 2; Discoidin domain-containing receptor 2; Discoidin domain-containing receptor tyrosine kinase 2; hydroxyaryl-protein; hydroxyaryl-protein kinase; MIG20a; migration-inducing gene 16 protein; neurotrophic tyrosine kinase receptor related 3; Neurotrophic tyrosine kinase, receptor-related 3; Ntrkr3; Receptor protein-tyrosine kinase TKT; RP11-572K18.1; Tkt; Tyro10; tyrosine-protein kinase TYRO 10; Tyrosine-protein kinase TYRO10; tyrosylprotein kinase
Gene Symbols Ddr2
Host Species Mouse
Immunogen This DDR2 antibody is generated from mice immunized with a KLH conjugated synthetic peptide between 290-320 amino acids from human DDR2.
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 4921
Target Species Human
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG1
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