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Invitrogen™ DDX1 Monoclonal Antibody (3E5B2)
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Catalog No. PIMA531711
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100 μL
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Catalog No. Quantity
PIMA531711 100 μL
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Catalog No. PIMA531711 Supplier Invitrogen™ Supplier No. MA531711
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Description

Mouse Monoclonal Antibody

MA5-31711 has been tested in indirect ELISA.

DDX1 (ATP-dependent RNA helicase DDX1) acts as an ATP-dependent RNA helicase. It is able to unwind both RNA-RNA and RNA-DNA duplexes. DDX1 possesses 5' single-stranded RNA overhand nuclease activity and ATPase activity on various RNA, but not DNA polynucleotides. DDX1, together with RELA, acts as a coactivator to enhance NF-kappa-b-mediated transcriptional activation. It also acts as a positive transcriptional regulator of cyclin CCND2 expression. It binds to the cyclin CCND2 promoter region. DDX1 is a component of a multi-helicase-TICAM1 complex that acts as a cytoplasmic sensor of viral double stranded RNA and plays a role in activation of a cascade of antiviral responses including the induction of proinflammatory cytokines via the adapter molecule TICAM1.
TRUSTED_SUSTAINABILITY

Specifications

Antigen DDX1
Applications ELISA, Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Monoclonal
Clone 3E5B2
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.05% sodium azide
Gene DDX1
Gene Accession No. Q92499
Gene Alias AA409185; ATP-dependent RNA helicase DDX1; DBP-RB; Ddx1; DEAD (Asp-Glu-Ala-Asp) box helicase 1; DEAD (Asp-Glu-Ala-Asp) box polypeptide 1; DEAD box polypeptide 1; DEAD box protein 1; DEAD box protein retinoblastoma; DEAD box-1; DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 1; DEAD/H-box helicase 1; UKVH5d
Gene Symbols DDX1
Host Species Mouse
Immunogen Purified recombinant fragment of human DDX1 (AA: 642-740) expressed in E. coli.
Purification Method Protein G
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 1653
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG1
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