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DDX1 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech
SDP

Catalog No. 501727089 Shop All Proteintech Group Inc Products
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50-172-7089 150 μL
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Catalog No. 50-172-7089 Supplier Proteintech Group Inc Supplier No. 113571AP150UL
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Description

Rabbit Polyclonal Antibody

DDX1 (ATP-dependent RNA helicase DDX1) acts as an ATP-dependent RNA helicase. It is able to unwind both RNA-RNA and RNA-DNA duplexes. DDX1 possesses 5′ single-stranded RNA overhand nuclease activity and ATPase activity on various RNA, but not DNA polynucleotides. DDX1, together with RELA, acts as a coactivator to enhance NF-kappa-b-mediated transcriptional activation. It also acts as a positive transcriptional regulator of cyclin CCND2 expression. It binds to the cyclin CCND2 promoter region. DDX1 is a component of a multi-helicase-TICAM1 complex that acts as a cytoplasmic sensor of viral double stranded RNA and plays a role in activation of a cascade of antiviral responses including the induction of proinflammatory cytokines via the adapter molecule TICAM1.

Specifications

Antigen DDX1
Applications Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Classification Polyclonal
Concentration 0.39 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
Gene DDX1
Gene Accession No. Q641Y8, Q91VR5, Q92499
Gene Alias DBP RB, DDX1, DEAD box protein 1, UKVH5d
Gene Symbols DDX1
Host Species Rabbit
Immunogen DDX1 Fusion Protein Ag1887
Purification Method Antigen Affinity Chromatography
Quantity 150 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 104721, 1653, 84474
Target Species Human, Mouse, Rat
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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