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DDX1 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech
SDP

Rabbit Polyclonal Antibody

Supplier:  Proteintech Group Inc 113571AP150UL

Encompass_Preferred

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Catalog No. 50-172-7089


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Description

Description

DDX1 (ATP-dependent RNA helicase DDX1) acts as an ATP-dependent RNA helicase. It is able to unwind both RNA-RNA and RNA-DNA duplexes. DDX1 possesses 5′ single-stranded RNA overhand nuclease activity and ATPase activity on various RNA, but not DNA polynucleotides. DDX1, together with RELA, acts as a coactivator to enhance NF-kappa-b-mediated transcriptional activation. It also acts as a positive transcriptional regulator of cyclin CCND2 expression. It binds to the cyclin CCND2 promoter region. DDX1 is a component of a multi-helicase-TICAM1 complex that acts as a cytoplasmic sensor of viral double stranded RNA and plays a role in activation of a cascade of antiviral responses including the induction of proinflammatory cytokines via the adapter molecule TICAM1.
Specifications

Specifications

DDX1
Polyclonal
Unconjugated
DDX1
DBP RB, DDX1, DEAD box protein 1, UKVH5d
Rabbit
Antigen Affinity Chromatography
RUO
104721, 1653, 84474
-20°C
Liquid
Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
0.39 mg/mL
PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
Q641Y8, Q91VR5, Q92499
DDX1
DDX1 Fusion Protein Ag1887
150 μL
Primary
Human, Mouse, Rat
Antibody
IgG
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