Invitrogen™ DDX10 Polyclonal Antibody

Catalog No.	Quantity
PIPA5100468	100 μL

Catalog No. PIPA5100468

Supplier: Invitrogen™ PA5100468

Description

Rabbit Polyclonal Antibody

Antibody detects endogenous levels of total DDX10.

DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. This gene encodes a DEAD box protein, and it may be involved in ribosome assembly. Fusion of this gene and the nucleoporin gene, NUP98, by inversion 11 (p15q22) chromosome translocation is found in the patients with de novo or therapy-related myeloid malignancies.

Specifications

• Antigen: DDX10
• Applications: Western Blot
• Classification: Polyclonal
• Concentration: 1 mg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
• Gene: Ddx10
• Gene Accession No.: Q13206, Q80Y44
• Gene Alias: 4632415A01Rik; AI646054; Ddx10; DDX10-NUP98 fusion protein type 2; DEAD (Asp-Glu-Ala-Asp) box polypeptide 10; DEAD box protein 10; DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 10 (RNA helicase); DEAD-box helicase 10; HRH-J8; probable ATP-dependent RNA helicase DDX10
• Gene Symbols: Ddx10
• Host Species: Rabbit
• Immunogen: A synthesized peptide derived from human DDX10(Accession Q13206), corresponding to amino acid residues M1-E49.
• Purification Method: Affinity chromatography
• Quantity: 100 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 1662, 300710, 77591
• Target Species: Human, Mouse, Rat
• Content And Storage: -20°C
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov