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Invitrogen™ DDX10 Polyclonal Antibody
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Catalog No. PIPA552086
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100 μL
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PIPA552086 100 μL
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Catalog No. PIPA552086 Supplier Invitrogen™ Supplier No. PA552086
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: KVPVKEIKIN PEKLIDVQKK LESILAQDQD LKERAQRCFV SYVRSVYLMK DKEVFDVSKL PIPEYALSLG LAVAPRVRFL QKMQKQPTKE LVRSQADKVI EPRAPSLTND EVEEFRAYFN EKMSILQKGG KRLEGTEHRQ DNDTGNEE Highest antigen sequence identity to the following orthologs: Mouse - 76%, Rat - 78%.

DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. This gene encodes a DEAD box protein, and it may be involved in ribosome assembly. Fusion of this gene and the nucleoporin gene, NUP98, by inversion 11 (p15q22) chromosome translocation is found in the patients with de novo or therapy-related myeloid malignancies.
TRUSTED_SUSTAINABILITY

Specifications

Antigen DDX10
Applications Immunohistochemistry (Paraffin), Immunocytochemistry
Classification Polyclonal
Concentration 0.2 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene Ddx10
Gene Accession No. Q13206
Gene Alias 4632415A01Rik; AI646054; Ddx10; DDX10-NUP98 fusion protein type 2; DEAD (Asp-Glu-Ala-Asp) box polypeptide 10; DEAD box protein 10; DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 10 (RNA helicase); DEAD-box helicase 10; HRH-J8; probable ATP-dependent RNA helicase DDX10
Gene Symbols Ddx10
Host Species Rabbit
Immunogen Recombinant protein corresponding to Human DDX10. Recombinant protein control fragment (Product #RP-102449).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 1662
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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