Invitrogen™ DDX10 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA552086

Catalog No. PIPA552086

Description

Immunogen sequence: KVPVKEIKIN PEKLIDVQKK LESILAQDQD LKERAQRCFV SYVRSVYLMK DKEVFDVSKL PIPEYALSLG LAVAPRVRFL QKMQKQPTKE LVRSQADKVI EPRAPSLTND EVEEFRAYFN EKMSILQKGG KRLEGTEHRQ DNDTGNEE Highest antigen sequence identity to the following orthologs: Mouse - 76%, Rat - 78%.

DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. This gene encodes a DEAD box protein, and it may be involved in ribosome assembly. Fusion of this gene and the nucleoporin gene, NUP98, by inversion 11 (p15q22) chromosome translocation is found in the patients with de novo or therapy-related myeloid malignancies.

Specifications

• Antigen: DDX10
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: Ddx10
• Gene Alias: 4632415A01Rik; AI646054; Ddx10; DDX10-NUP98 fusion protein type 2; DEAD (Asp-Glu-Ala-Asp) box polypeptide 10; DEAD box protein 10; DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 10 (RNA helicase); DEAD-box helicase 10; HRH-J8; probable ATP-dependent RNA helicase DDX10
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 1662
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Immunocytochemistry
• Concentration: 0.2 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: Q13206
• Gene Symbols: Ddx10
• Immunogen: Recombinant protein corresponding to Human DDX10. Recombinant protein control fragment (Product #RP-102449).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov